Nail Infections: Signs and Symptoms

  • Pain at rest or when holding objects
  • Green or yellow discoloration under the nails
  • Oozing of foul-smelling fluid from under the nails
  • Redness, swelling, or "pus pockets" around the nail

 

Treating Infections

Once changes in your nail occur, the risk of infection may increase, especially if the nails become loose there is any redness or swelling in the skin around the nails. Infections under and around the nails are more frequently caused by cetuximab, docetaxel, erlotinib lapatinib, paclitaxel, and panitumumab. So be sure to alert your health care team if, during treatment, you notice any signs of a nail infection. Using a topical antibiotic (Polysporin or mupirocin) or an antiseptic (povidone-iodine) ointment daily is a good way to fight off nail infections early on. If the infection is painful, your doctor may prescribe two-week course of oral antibiotics such as cephalexin or ciprofloxacin.

 

Treatment Path

Degree

Grade 1

Chemotherapy can be continued at the same dose/frequency, Daily application of topical antibiotic (Polysporin, mupirocin) OR antiseptic (povidone-iodine) ointment, Reassess in 2 weeks; if it worsens or does not improve, proceed to the next step


Grade 2

Chemotherapy can be continued at the same dose/frequency, Oral antibiotics (cephalexin, ciprofloxacin) AND topical antiseptic (povidone-iodine)Ointment AND chemical cauterization or cryotherapy by a Dermatologist,Reassess in 2 weeks, if it worsens or does not improve, proceed to the next step by your oncologist, Oral antibiotics (cephalexin, ciprofloxacin) AND partial/complete nail removal or chemical cauterization or cryotherapy by a dermatologist


Grade 3

Chemotherapy may be interrupted or decreased, Reassess in 2 weeks, if it worsens or does not improve your oncologist may change or decrease chemotherapy